While not for everyone, significant improvement is seen in about 80% of people who follow immuno-therapy. The biggest drawback to having allergy shots is that they can be inconvenient, as typically, the tiny injections are given twice weekly for six months, then every three to four weeks for three to five years. And, unfortunately, because of the nature of the therapy, adverse reactions are common, although serious adverse reactions are very rare. This is because the serum you are given in the injections is made from extracts of the items you are actually allergic to. And, while immuno-therapy is not a cure for allergies, it is considered more effective than medication alone because it treats the cause of your allergic reactions, not just the symptoms. And, every day, newer, more accurate, and safer forms of immuno-therapy are being developed.
OTHER POTENTIAL SOLUTIONS FOR ALLERGY SUFFERERS:
Bathing your cat! A new study done at the University of Virginia Asthma and Allergic Diseases Center in Charlottesville has suggested that frequently bathing your feline could reduce the shedding of allergy-irritating proteins (Fel d 1). "The major findings of the paper are that even though the allergen levels are reduced, they are not maintained at low levels for long periods of time so you would have to repeatedly bath the cat - which may not be that feasible for the patient," said senior investigator Dr. Judith Woodfolk. "The findings were not negative - and that is important - but it was just that you would have to continue to bath the cat, maybe every two to four weeks," she continued. Cats washed with soap, water and a hose had a 44% decrease in an allergy-causing protein, while those totally immersed in tap water had a 79% reduction in allergen level in the week after the washing.
SYNTHETIC EPITOPE VACCINE:
Researchers at the John Hopkins University School of Medicine were recently conducting trials with an epitope vaccine developed from the cat dander allergen Fel d 1. The vaccine consisted of two 27 amino acid peptides derived from Fel d 1. A majority of the patients in the study (71%) receiving four weekly injections of 750 ug, showed improvements, and a follow-up study of the participants showed that 75% of those who had received that regimen continued to maintain some or all of their improvement after seven and a half months.
The idea of using allergen extracts to treat allergies is not a new one... It was in the year 1911 that this idea was first reported. In the 1970's, this idea evolved into an immuno-therapy with allergen extracts that worked by increasing suppressor T-cells (which then controlled the production of the IgE antibody). It has only been in the past ten years that researchers have created T-cell epitopes to actually block IgE receptors, which then block the allergic cascading reaction.
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